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2 Levodopa remains the mainstay for the treatment of PD and is referred to as the gold standard

This suggests your gut develops adaptive mechanisms that partially counteract the medication's slowing effect

Based on a 5-km time improvement of 2.5% or about 30 seconds (SD = 1 minute) with Protandim , and no improvement in the placebo group, about 34 runners in total were needed (Effect size for ANOVA = f = 0.25, which is moderate, statistical power = 80%, two-sided alpha error probability = 5%, two measurements per group, two groups, correlation amongst repeated measures = 0.50, F-test Family, ANOVA repeated measures, within-between interaction, G*Power 3.1.2, Universitt Kiel, Germany)